Bradley D. Clymer
Associate Professor of Electrical &
Computer Engineering
Associate Professor of Biomedical
Informatics
The Ohio State University
Mailing Address:
205 Dreese Laboratory
Department of Electrical & Computer Engineering
2015 Neil Avenue
Columbus, OH 43210 USA
phone: (614) 292-3477 (office, with machine)
fax: (614) 292-7596
email: clymer.1@osu.edu
Office Hours (August 23-December 6, 2023):
MWF 2:00-3:30 pm, Th 10:30am-12:30 pm
or by appointment (check schedule below for openings)
This week's
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Next
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Biography
Prof. Clymer received the
B.S.E.E. and M. S. degrees in electrical engineering from The Ohio State
University in 1981 and 1982, respectively, and the Ph. D. degree in electrical
engineering from Stanford University in 1987. From 1981 to 1983 he worked in
the Advanced Subsystems Department of Hughes Aircraft Company Space and
Communications Group in El Segundo, California. He has been on the faculty of
Electrical & Computer Engineering at OSU since 1987. He has been
Participating Faculty (1991-2005) and Core Faculty (2005-present) in Biomedical
Engineering at OSU, and has held a faculty appointment in the Department of
Biomedical Informatics at OSU since 2002.
Prof. Clymer worked as a consultant for 10 years for The Cleveland Clinic Foundation, Cleveland, Ohio, on adaptive image processing of xray images, 3D reconstruction of transesophageal ultrasound images of cardiac valves, 3D reconstruction of mammograms, feasibility of MRI for imaging aortic atherosclerotic plaques and classification of atherosclerotic plaques from texture analysis of intravascular ultrasound (IVUS) images of coronary arteries, signal analysis and data fusion (EEG, EKG, EMG, etc.) for overnight sleep studies, cone beam reconstruction for a x-ray computed tomographic microscope, and image texture analysis of trabecular structures for assessment of osteoporosis and prediction of fracture. He has an Adjunct Staff appointment in the Department of Biomedical Engineering at The Cleveland Clinic Foundation.
Dr. Clymer is a senior member of IEEE.
Research Interests
Dr. Clymer's current research
activities are processing and capture of medical images, including MRI,
mammography, ultrasound and x-ray computed tomographic microscopy; signal
processing of EEG, ECG and phonocardiographs; adaptive filtering; signal
processing to simulate human perception of audio for synchronization of
movement for a biped robot; and Fourier transforms and linear systems.
Courses Taught
Prof. Clymer has taught a wide
range of courses, including ECE 5206 Medical Imaging, which runs every spring
semester. He also occasionally teaches ECE 2050, (Introduction to discrete time
systems and signals), and ECE 3050 (linear systems).
Publications
R.
Mazumder, S. Schroeder, X. Mo, A. S. Litsky, B. D. Clymer, R. D. White, A. Kolipaka,
`` In vivo magnetic resonance elastography to estimate left ventricular
stiffness in a myocardial infarction induced porcine model,'' J. Magn. Reson. Imaging, August 2016,
doi:10.1002/jmri.25432.
R.
Mazumder, S. Schroeder, X. Mo, B. D., Clymer, R. D. White, A. Kolipaka,
``In vivo quantification of myocardial stiffness in hypertensive porcine
hearts using MR elastography,'' J. Magn. Reson. Imaging, August 2016, doi:10.1002/jmri.25423.
H.
Hemami, Eric Tarr, Boren Li, A. Krishnamurthy, B. Clymer, B. Dariush, ``Toward
a Cybernetic Model of Human Movement," Mechanical Engineering Research,
vol. 6, no. 1, pp. 29-45, 2016.
R.
Mazumder, B. Clymer, X. Mo, R.D. White,
A. Kolipaka, ``Adaptive Anisotropic Gaussian Filtering to Reduce Acquisition
Time in Cardiac Diffusion Tensor Imaging,''
International Journal of Cardiovascular Imaging, vol. 32, no. 6, pp. 921--934, 2016.
R
Mazumder, S Choi, BD Clymer, RD White, A Kolipaka, `` Diffusion Tensor Imaging of Healthy and
Infarcted Porcine Hearts: Study the Impact of Formalin-Fixation,'' Journal of
Medical Imaging and Radiation Sciences,
vol. 47, no. 1, pp. 74--85, 2016.
Carlos
del Rio, Bradley D Clymer, George Billman, ``Myocardial Electrotonic
Response to Submaximal Exercise in Dogs with Healed Myocardial Infarctions:
Evidence for beta-Adrenoceptor Mediated Enhanced Coupling during Exercise
Testing," Frontiers in Physiolology, vol. 6, doi:10.3389/fphys.2015.00025,
2015.
Niranchana
Manivannan, Bradley D. Clymer, Anna Bratasz, Kimerly A. Powell,``Comparison of Super
Resolution Reconstruction Acquisition Geometries for Use in Mouse
Phenotyping," International Journal of Biomedical Imaging, vol. 2013,
Article ID 820874, 11 pages, 2013. doi:10.1155/2013/820874.
TP
Sharkey-Toppen, G Miha, A Maiseyeu,
T Tran, BD Clymer, OP Simonetti,
SV Raman, ``Improved in vivo human carotid artery wall T2*
estimation," Magnetic Resonance Imaging, vol. 31, no. 1, pp. 44--52, 2013.
H.
Hemami, B.D. Clymer M.
Hemami, ``Simulation of Control and Synthesis of a Constrained Movement towards
Rehabilitation Exercises," Integrated Computer-Aided Engineering, vol. 19,
no. 4, pp, 351--364, 2012.
Barbaros
S. Erdal, Bradley D. Clymer, Vedat Yildiz, Michael V. Knopp, Elliott D. Crouser, ``Unexpectedly High
Prevalence of Sarcoidosis in a Representative U.S. Metropolitan
Population," Respiratory Medicine, vol. 106, no. 6, pp. 893--899, 2012.
Selnur
Erdal, Elliott D. Crouser, Vedat Yildiz, Mark A. King, Andrew T. Patterson, Michael V. Knopp, Bradley D. Clymer, ``Quantitative
Computerized Two-Point Correlation Analysis of Lung CT Scans Correlates with
Pulmonary Function in Pulmonary Sarcoidosis," Chest, vol. 142, no. 6, pp.
1589--1597, 2012.
Selnur
Erdal, Jianhua Liu, Jing Ding,
Jingchun Chen, Clay B.
Marsh, Jyoti Kamal, Bradley D. Clymer, ``A Database
De-identification Framework to Enable Direct Queries on Medical Data for
Secondary Use,"Methods of Information in Medicine, vol. 51, no. 3, pp.
229--241, 2012.
Carlos
del Rio, Tom Dawson, Bradley Clymer, David Paterson, George Billman, ``Effects of Acute Vagal
Nerve Stimulation on the Early Passive Electrical Changes Induced by Myocardial
Ischaemia in Dogs: Heart Rate-mediated Attenuation," Experimental
Physiology, vol. 93, no. 8, pp. 931--944, 2008.
Mehmet
Kale, Bradley Clymer, Regina Koch,
Steffen Sammet, Robert Stevens, Michael Knopp, ``Multispectral Co-occurrence
With Three Random Variables in Dynamic Contrast Enhanced Magnetic Resonance
Imaging of Breast Cancer," IEEE Trans. Medical Imaging, vol. 27, no. 10,
pp 1425--1431, 2008.
Carlos
del Rio, Patrick McConnell, Monica Kukielka, Roger Dwonczyk, Bradley
Clymer, Michael Howie, George Billman, ``Electrotonic Remodeling
following Myocardial Infarction in Dogs Susceptible and Resistant to Sudden
Cardiac Death," J. Appl. Physiology, vol. 104, no. 2, pp. 386--393, 2008.
Hee Chun, Bradley Clymer,
Steffen Sammet, Regina M.
Koch, Robert Stevens, Michael V. Knopp,
``Improvement of ROI Placement by Adding Auditory Feedback to Radiological
Complex Tumor Cases: A Pilot Assessment using DCE-MR Mammography,'' J Magnetic Resonance Imaging, vol. 27, no. 1,
pp. 27--33, 2008.
Rizwan Ahmad, Deepti S. Vikram, Bradley Clymer, Lee C.
Potter, Yuanmu Deng, Parthasarathy Srinivasan, Jay L. Zweier, Periannan
Kuppusamy, ``Uniform Distribution of Projection Data for Improved
Reconstruction Quality of 4D EPR Imaging,''
J. Magn. Reson, vol. 187, no. 2, pp. 277-287, 2007.
Brent J. Woods, Bradley D. Clymer, Tahsin Kurc, Johannes
Heverhagen, Robert Stevens, Adem Orsdemir, Orhan Bulan, Michael Knopp, “Malignant Lesion Segmentation Using 4D Co-occurrence
Texture Analysis Applied to Dynamic Contrast Enhanced Magnetic Resonance Breast
Image Data,” J. Magnetic Resonance Imaging, vol. 25, no. 3, pp.495–501, 2007.
Rizwan Ahmad, Yuanmu Deng, Deepti S. Vikram,
Bradley Clymer, Parthasarathy Srinivasan, Jay L. Zweier, Periannan Kuppusamy,
“Quasi Monte Carlo-based isotropic distribution of gradient directions for
improved reconstruction quality of 3D EPR imaging,” J. Magnetic Resonance, vol.
184, no. 2, pp. 236–245, 2007.
Rizwan Ahmad, Bradley Clymer, Deepti S. Vikram,
Yuanmu Deng, Hiroshi Hirata, Jay L. Zweier, Periannan Kuppusamy, “Enhanced
Resolution for EPR Imaging by Two-Step Deblurring,” J. Magnetic Resonance, vol.
184, no. 2, pp. 246--257, 2007..
Brent Woods, Bradley Clymer, Johannes
Heverhagen, Michael Knopp, Joel Saltz, Tahsin Kurc, “Parallel 4-D Haralick
Texture Analysis for Disk-resident Image Datasets,” Concurrency and
Computation: Practice and Experience, vol. 19, pp. 65--87, 2007.
Rizwan Ahmad, Deepti S. Vikram, Sergey
Petryakov, Yuanmu Deng, Jay L. Zweier, Periannan Kuppusamy, Bradley Clymer,
“Automated on-the-fly detection and correction procedure for EPR imaging data
acquisition,” Magn. Reson. in Med., vol. 56, no. 3, pp. 644--653, 2006.
Rizwan Ahmad, Bradley Clymer, Yuanmu Deng,
Guanglong He, Deepti S. Vikram, Jay L Zweier, and Periannan Kuppusamy,
“Optimization of Data Acquisition for EPR Imaging,” J. Magnetic Resonance, vol.
179, no. 2, pp. 263--272, 2006.
Chad Showalter, Bradley Clymer, Bradford
Richmond and Kimerly Powell, “Three dimensional texture analysis of cancellous
bone cores evaluated at clinical CT resolutions,” Osteoporosis International,
vol. 17, no. 2, pp. 259--266, 2006.
Carlos del Rio, Patrick McConnell, Bradley
Clymer, Roger Dzwonczyk, Robert Michler, George Billman and Michael Howie,
“Early time course of myocardial electrical impedance duringacute coronary
artery occlusion in pigs, dogs and man,” J. Applied Physiology, vol. 99, no. 4,
pp. 1576--1581, 2005.
T.-K. Truong, B. D. Clymer, D. W. Chakeres and
P. Schmalbrock, “Three-dimensional numerical simulations of
susceptibility-induced magnetic field inhomogeneities in the human head,” Magn.
Reson. Imag., vol. 20, pp 759-770, 2002.
D. James, B. D.
Clymer and P. Schmalbrock, “Texture detection of simulated microcalcification
susceptibility effects in magnetic resonance imaging of breasts,” J. Magn.
Reson. Imag., vol. 13, no. 6, pp. 876--881, 2001.
A. Bartolo, B. D.
Clymer, R. C. Burgess, J. P. Turnbull, J. A. Golish and M. Perry, “An
arrhythmia detector and heart rate estimator for overnight polysomnography
studies,” IEEE Trans. Biomed. Eng.},
vol. 48, no. 5, pp. 513--521, 2001.
A. Bartolo, B. D. Clymer,
J. A. Golish and R. C. Burgess, “The polysomnogram assay (PSGA): A method to represent the overnight
polysomnogram in a condensed format,” Computers \& Biomedical
Research, vol. 33, no. 2, pp. 110--125,
2000.
B. L. Anderson, L.
J. Pelz, S. A. Ringel, B. D.Clymer and S. A. Collins, Jr., “Photonics
laboratory with emphasis on technical diversity,” IEEE Trans. Educ., vol. 41,
no. 3, pp. 194--202, 1998.
A. Bartolo, B. D. Clymer, R. Burgess and
J.Turnbull, “An efficient method of FIR
filtering based on impulse response rounding,” IEEE Trans. Sig. Proc.,
vol. 46, no. 8, pp. 2243--2248, 1998.
K. Iqbal, B. D. Clymer and H. Hemami, “Squatting
maneuver of a three-link nine-muscle model in the saggital plane,” J. Aut.
Control, vol. 7, pp. 113--129, 1997.
L. Jalics, H. Hemami, and B. D. Clymer, “Rocking,
Tapping and Stepping: a Prelude to Dance,” Autonomous Robots, vol. 4, no. 3,
pp. 227--242, 1997.
L. Jalics, H. Hemami, and B. D. Clymer, “Control
Strategy for Adaptive Bipedal Locomotion,” Autonomous Robots, vol. 4, no. 3,
pp. 243--258, 1997.
Kui Ying, Bradley D. Clymer and Petra Schmalbrock,
“Adaptive filtering for high resolution magnetic resonance imaging,” J. Mag.
Res. Imag., vol. 6, no. 2, pp. 367--377, 1996.
Dane C. Butzer, Bradley D. Clymer, and Betty Lise
Anderson, “A high efficient interconnection for use with a multistage optical
switching network with orthogonally polarized data and address information,”
Applied Optics, vol. 35, no. 11, pp. 1788--1800, 1995.
K. Ying, P. Schmalbrock and B. Clymer, “Echo-time
reduction for submillimeter resolution imaging with a 3D phase encode time
reduced acquisition method,” Mag. Res. in Med., vol. 33, pp. 82--87, 1995.
John H. Gossett, Bradley D. Clymer and Hooshang
Hemami, “Long and Short Delay Feedback on One-Link Nonlinear Forearm with
Coactivation,” IEEE Trans.on Syst., Man & Cyber., vol. 24, no. 9, pp
1317--1327, 1994.
P. Schmalbrock, M. A. Brogan, D. W. Chakeres, V. A
Hacker, K. Ying, and B. Clymer, “Optimization of Sub-Millimeter Resolution MR
Imaging Methods for the Inner Ear,” J. Mag. Res. Im., vol. 3, no. 3, pp.
451--459, 1993.
Betty Lise Anderson, Thomas B. DeVore and Bradley
D. Clymer, “Use of Laser Diode Arrays in Holographic Interconnects,” Appl. Opt.
vol. 31, no. 35, pp. 7411--7416, 1992.
R. Brian Jenkins and Bradley D. Clymer,
“Acousto-optic Comparison Switch for Optical Switching Networks with Analog
Addressing Techniques,” Appl. Opt., vol. 31, no. 26, pp. 5453--5463, 1992.
B. D. Clymer, T. B. De Vore, J. Jagadeesh, and L.
D. Tomei, “Spatial Resolution of Images Reconstructed from Bulk Detection
Scanning Laser Microscope,” Appl. Opt., vol. 30, no. 34, pp. 5056--5062, 1991.
B. D. Clymer and Dana C. Gillfillan, “Corrugation
Gratings for Fast Integrated CMOS Photodetectors: Implementation and
Diffraction Analysis,” Appl. Opt., vol. 30, no. 30, pp. 4390--4395, 1991.
Bradley D. Clymer, “Reflected Sunlight Reduction
and Characterization for Deep Space Optical Receiver Antenna (DSORA),” NASA
Telecomm. and Data Aquis. Prog. Report, vol. 42-103, pp. 110--117, 1990.
Bradley D. Clymer, “Active Optic1s for Segmented
Primary Mirror on Deep Space Optical Receiver Antenna (DSORA),” NASA Telecomm.
and Data Aquis. Prog. Report, vol. 42-103, pp. 128--134, 1990.
Bradley D. Clymer, “Surface-Relief Grating
Structures for Efficient High Bandwidth Integrated Photodetectors for Optical
Interconnections in Silicon VLSI,” Appl. Opt., vol. 28, no. 24, pp. 5374--5382,
1989.
Bradley D. Clymer and Joseph W. Goodman, “Timing
Uncertainty for Receivers in Optical Clock Distribution for VLSI,” Opt. Eng.,
vol. 27, no. 11, pp. 944--954, 1988.
Bradley D. Clymer and Joseph W. Goodman, “Optical
Clock Distribution to Silicon Chips,” Opt. Eng., vol. 25, no. 10, pp. 1103--1108,
1986.
B. Clymer and S. A. Collins, Jr., “Optical
Computer Switching Network,” Opt. Eng., vol. 24, no. 1, pp. 74--81, 1985.
Personal Interests
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